Some sorta rapture happens, the majority of people are left on earth and space, and we decide to take revenge on heaven for the apocalypse. Like, building theological weaponry with advanced tech stuff, and fucking, killing gods. Maybe with an alliance with hell for a bit for good measure!
Picture related (source: https://www.deviantart.com/mus0u/art/Skyborn-Juggernaut-315032323 )