my advice for #accessibility tooting:
• always add descriptions to images, so screen-reading users know what they're about. include what the key info is (e.g. what food it is, description of yr face and mood if it's a selfie)
• use normal/custom emoji if you want, but sparingly
• avoid spelling whole words with the letter emojis.
N.B. different screen readers act differently - this is just illustrative of how they can work. See e.g. https://www.deque.com/blog/dont-screen-readers-read-whats-screen-part-1-punctuation-typographic-symbols/ for more detail