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  1. Sim Bot (sim@sealion.club)'s status on Tuesday, 27-Nov-2018 19:54:20 EST Sim Bot Sim Bot
    I wonder what @thatbrickster thinks of this video: https://www.youtube.com/watch?v=9iVFPVTBNaw
    In conversation Tuesday, 27-Nov-2018 19:54:20 EST from sealion.club permalink

    Attachments

    1. Invalid filename.
      Memory Loss and the Hippocampus: MUST WATCH!
      By Dr. Eric Berg DC from YouTube
    1. Mister M. T. Sack (thatbrickster@shitposter.club)'s status on Wednesday, 28-Nov-2018 07:05:49 EST Mister M. T. Sack Mister M. T. Sack
      in reply to
      @sim I don't like Dr. Eric Berg but we'll see.
      In conversation Wednesday, 28-Nov-2018 07:05:49 EST from shitposter.club permalink
      1. Mister M. T. Sack (thatbrickster@shitposter.club)'s status on Wednesday, 28-Nov-2018 07:51:42 EST Mister M. T. Sack Mister M. T. Sack
        in reply to
        @sim
        >mother eating [...] a lot of carbs
        He's a keto evangelist so that's not surprising to hear.

        >you destroy the hippocampus with too much insulin and high sugar in the diet
        Not quite right about the sugar part. Diets high in animal fat cause insulin resistance, which then throws blood sugar and insulin regulation into disarray. That is what causes the thing he's describing.
        Also, a study on rodents, "Insulin resistance within the telencephalon may underlie the cognitive deficits commonly reported to accompany type 2 diabetes." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878207/ (no conflicts of interest documented)

        >if you're pregnant, make sure to keep the carbs to a normal level
        He's deliberately misrepresenting what 'carbs' are. Carbs are pasta, cereals, rice and tubers to name a few. Additional or 'free' sugars are refined carbs but they are not *the* carbs.

        >recommends breast milk or making your own formula
        This is actually good advice.

        >fasting is the [best] way of regrowing your brain
        Fasting may raise levels of cortisol, the stress hormone, which may have a negative effect. However, there are hypotheses suggesting how fasting may stimulate growth. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411899/ (no conflicts of interest declared)

        >aerobic exercise
        Agree. BDNF is stimulated through exercise (non-scientific proof is how you can starve off hunger when you're active) and can help relieve stress. (Another rodent study) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915811/ (no conflicts of interest documented)

        >you become B1 deficient by eating too many refined carbs
        You become deficient by not eating at all or those lacking in B1. Refined carbs are not a food, they make up the product. Apparently, raw fish is an example that may destroy B1 via enzymes but excess alcohol intake is the main cause.

        >avoid stress, easier said than done
        Agree.

        >your brain loves ketones
        No evidence to suggest that. I did find a study from 2016 suggesting ketosis may help with Alzheimer's however there is a declared conflict of interest. I therefore consider it a 'junk' study. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937039/

        >because they put less stress on the brain
        The above 'junk' study suggests uptake of glucose lowers with age and that ketones would serve better. More independent research is needed to confirm that.
        In conversation Wednesday, 28-Nov-2018 07:51:42 EST from shitposter.club permalink

        Attachments

        1. Invalid filename.
          Hippocampal memory processes are modulated by insulin and high-fat-induced insulin resistance
          from PubMed Central (PMC)
          Insulin regulates glucose uptake and storage in peripheral tissues, and has been shown to act within the hypothalamus to acutely regulate food intake and metabolism. The machinery for transduction of insulin signaling is also present in other brain areas, ...
        2. Invalid filename.
          Brain-derived neurotrophic factor as a regulator of systemic and brain energy metabolism and cardiovascular health
          from PubMed Central (PMC)
          Overweight sedentary individuals are at increased risk for cardiovascular disease, diabetes, and some neurological disorders. Beneficial effects of dietary energy restriction (DER) and exercise on brain structural plasticity and behaviors have been demonstrated ...
        3. Invalid filename.
          Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate
          from PubMed Central (PMC)
          Exercise induces beneficial responses in the brain, which is accompanied by an increase in BDNF, a trophic factor associated with cognitive improvement and the alleviation of depression and anxiety. However, the exact mechanisms whereby physical exercise ...
        4. Invalid filename.
          Can Ketones Help Rescue Brain Fuel Supply in Later Life? Implications for Cognitive Health during Aging and the Treatment of Alzheimer’s Disease
          from PubMed Central (PMC)
          We propose that brain energy deficit is an important pre-symptomatic feature of Alzheimer’s disease (AD) that requires closer attention in the development of AD therapeutics. Our rationale is fourfold: (i) Glucose uptake is lower in the frontal ...
        1. Mister M. T. Sack (thatbrickster@shitposter.club)'s status on Wednesday, 28-Nov-2018 07:55:55 EST Mister M. T. Sack Mister M. T. Sack
          in reply to
          @sim Fasting study is a rodent one too. I want studies on humans, damn it!
          In conversation Wednesday, 28-Nov-2018 07:55:55 EST from shitposter.club permalink
        2. Sim Bot (sim@sealion.club)'s status on Wednesday, 28-Nov-2018 08:57:01 EST Sim Bot Sim Bot
          in reply to
          @thatbrickster "Not quite right about the sugar part. Diets high in animal fat cause insulin resistance, which then throws blood sugar and insulin regulation into disarray. That is what causes the thing he's describing." That is interesting to hear. I guess if you want to avoid this problem, you want a diet that isn't high in animal fat.

          "He's deliberately misrepresenting what 'carbs' are. Carbs are pasta, cereals, rice and tubers to name a few. Additional or 'free' sugars are refined carbs but they are not *the* carbs." I really like the carbs above... don't think that I could go without them! But I will eventually really need to think about my diet when I am trying to get pregnant. I want to give my children the best advantages in life because life will tear them down. I didn't get the resiliency that I hope to give them. 
          "This is actually good advice." I really did like this advice about breastfeeding or making your own formula. Also when he says to not rely on synthetic vitamins... to get it sourced from whole foods I think it would be. Can't recall his actual words. But he does recommend yeast!
          But yeah, I did wonder what you would make of them. I'm not sure about the fasting and ketones stuff. Although I do accidentally end up fasting through the night and morning at times. ;;
          In conversation Wednesday, 28-Nov-2018 08:57:01 EST from sealion.club permalink
      2. Sim Bot (sim@sealion.club)'s status on Wednesday, 28-Nov-2018 08:43:52 EST Sim Bot Sim Bot
        in reply to
        @thatbrickster Ah... come across him before? What makes you not like him?
        In conversation Wednesday, 28-Nov-2018 08:43:52 EST from sealion.club permalink
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