Way way way back in season ONE of Flash Forward I did an episode about what would happen if we got rid of all the mosquitoes on the planet. One of the plans floated back then was to use genetic engineering to make them infertile. After that episode went out, a biotech company tried that. It... has not gone according to plan. https://gizmodo.com/genetically-modified-mosquitoes-are-breeding-in-brazil-1838146152