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Notices by Canageek (canageek@cybre.space), page 5

  1. Canageek (canageek@cybre.space)'s status on Tuesday, 23-Jul-2019 23:07:38 EDT Canageek Canageek
    • chr

    @chr .....Can't tell if trolling or just an image I can't see

    In conversation Tuesday, 23-Jul-2019 23:07:38 EDT from cybre.space permalink
  2. Canageek (canageek@cybre.space)'s status on Tuesday, 23-Jul-2019 12:37:47 EDT Canageek Canageek
    • Mara, playing Magic
    • Brye, Fancy Hat Trickster

    @DialMforMara @SliverQueen I used to have this with regards to D&D rules. It didn't help that the AD&D rules never made much sense...

    In conversation Tuesday, 23-Jul-2019 12:37:47 EDT from cybre.space permalink
  3. Lyn Thorne🍁Autumn 🍂 (aldersprig@tootplanet.space)'s status on Monday, 22-Jul-2019 09:27:58 EDT Lyn Thorne🍁Autumn 🍂 Lyn Thorne🍁Autumn 🍂

    From https://twitter.com/urbanfriendden

    instead of "sir/madam", consider "traveller"

    - gender neutral
    - fun to say
    - acknowledges the endless journey of the soul
    - makes you feel like a medieval tavernkeep
    - you absolutely can't risk misgendering a wandering swordmaster

    In conversation Monday, 22-Jul-2019 09:27:58 EDT from tootplanet.space permalink Repeated by canageek
  4. DialMforMara (dialmformara@wandering.shop)'s status on Monday, 22-Jul-2019 00:55:45 EDT DialMforMara DialMforMara

    My thoughts about #KingdomHearts, copied from Discord

    It scratches my complexity itch. Also my beautiful anime boys itch.

    Like seriously you need to get deep into the weeds for it to make sense, and it's both transcendent & amazingly stupid

    But if you want a story about two boys who love each other helping each other deal with mental illness and breaking an ancient cycle of violence, it's worth your time. Just be ready to skip the terribly written Disney sections when they get to be too much.

    In conversation Monday, 22-Jul-2019 00:55:45 EDT from wandering.shop permalink Repeated by canageek
  5. Canageek (canageek@cybre.space)'s status on Sunday, 21-Jul-2019 14:52:20 EDT Canageek Canageek
    • katt, sky-guided 🌈🌌

    @starkatt Mentioned at the start of a talk by Richard Gillilan I'm in right now. They've detected the signature of life firm there, but not live itself yet. Highest pressure life they've found is 120 MPa.

    In conversation Sunday, 21-Jul-2019 14:52:20 EDT from cybre.space permalink
  6. Canageek (canageek@cybre.space)'s status on Sunday, 21-Jul-2019 14:40:46 EDT Canageek Canageek

    They also think the most recent common ancestor of ask life on earth might have lived at hydrothermal vents, due to some common, strange genes that occur in septate branches of the tree of Life that make the most sense down there.

    In conversation Sunday, 21-Jul-2019 14:40:46 EDT from cybre.space permalink
  7. Canageek (canageek@cybre.space)'s status on Sunday, 21-Jul-2019 14:38:52 EDT Canageek Canageek

    They think there might be life at the bottom of a subduction zone at the bottom of the Marianas Trench, 340 MPa pressure.

    In conversation Sunday, 21-Jul-2019 14:38:52 EDT from cybre.space permalink
  8. Canageek (canageek@cybre.space)'s status on Sunday, 21-Jul-2019 14:02:22 EDT Canageek Canageek
    • Ferdi Groenewald

    @ferds Cincinnati/Northern Kentucky

    In conversation Sunday, 21-Jul-2019 14:02:22 EDT from cybre.space permalink
  9. Canageek (canageek@cybre.space)'s status on Sunday, 21-Jul-2019 12:17:23 EDT Canageek Canageek
    • DialMforMara
    • Ɠεɱɩoɠ

    In case anyone wonders what scientific conferences are like, here is my plan for the week. #RealTimeChem #Crystallography #ACA2019 @gemlog @DialMforMara

    In conversation Sunday, 21-Jul-2019 12:17:23 EDT from cybre.space permalink
  10. Space·Time Will Tell (yoric@tabletop.social)'s status on Sunday, 21-Jul-2019 09:34:45 EDT Space·Time Will Tell Space·Time Will Tell

    Does anyone know of a service I could use to share files securely with non-technical people? Something like Dropbox, except I want to be able to trust it :)

    Preferably open-source, cross-platform.

    In conversation Sunday, 21-Jul-2019 09:34:45 EDT from tabletop.social permalink Repeated by canageek
  11. Canageek (canageek@cybre.space)'s status on Sunday, 21-Jul-2019 11:12:10 EDT Canageek Canageek
    • DialMforMara

    Awww, @DialMforMara 's post makes me want to hug her, but I am 3 time zones away

    In conversation Sunday, 21-Jul-2019 11:12:10 EDT from cybre.space permalink
  12. Canageek (canageek@cybre.space)'s status on Sunday, 21-Jul-2019 11:03:33 EDT Canageek Canageek
    • DialMforMara
    • OldBrushNewPaper

    @OldBrushNewPaper @DialMforMara https://cybre.space/@Canageek/102477292094495412

    In conversation Sunday, 21-Jul-2019 11:03:33 EDT from cybre.space permalink

    Attachments

    1. File without filename could not get a thumbnail source.
      New status by Canageek
      By Canageek from cybre.space
  13. 🍊oranje🍊 (oranje@cybre.space)'s status on Sunday, 21-Jul-2019 10:57:17 EDT 🍊oranje🍊 🍊oranje🍊

    The problem with screwing into #3Dprinted standoffs with screws. No matter the print orientation, screw threads are putting stress between layer lines. I've decided I like a captive nut on the back side so the screw's tension is actually compressing layers together rather than pulling them apart.

    In conversation Sunday, 21-Jul-2019 10:57:17 EDT from cybre.space permalink Repeated by canageek
  14. Canageek (canageek@cybre.space)'s status on Saturday, 20-Jul-2019 23:36:25 EDT Canageek Canageek
    • Mara, playing Magic
    • Brye, Fancy Hat Trickster

    @SliverQueen @DialMforMara That is one of the coolest ideas I've heard in ages. Also, realized I should be using either of my other two counts for this.

    In conversation Saturday, 20-Jul-2019 23:36:25 EDT from cybre.space permalink
  15. Canageek (canageek@cybre.space)'s status on Saturday, 20-Jul-2019 23:30:43 EDT Canageek Canageek
    • Mara, playing Magic
    • Brye, Fancy Hat Trickster

    @DialMforMara @SliverQueen It was my first guess, while you where worried about it being more dark scary fey

    In conversation Saturday, 20-Jul-2019 23:30:43 EDT from cybre.space permalink
  16. Canageek (canageek@cybre.space)'s status on Saturday, 20-Jul-2019 23:30:06 EDT Canageek Canageek
    • Mara, playing Magic

    @DialMforMara I WAS RIGHTTTTTTTTTTTTT :D :D :D :D

    In conversation Saturday, 20-Jul-2019 23:30:06 EDT from cybre.space permalink
  17. Canageek (canageek@cybre.space)'s status on Saturday, 20-Jul-2019 23:29:49 EDT Canageek Canageek
    • Mara, playing Magic
    • Brye, Fancy Hat Trickster

    @SliverQueen @DialMforMara WAIT. WAS I RIGHT ABOUT IT BEING A KING AURTHER SET?!

    In conversation Saturday, 20-Jul-2019 23:29:49 EDT from cybre.space permalink
  18. Canageek (canageek@cybre.space)'s status on Saturday, 20-Jul-2019 23:28:55 EDT Canageek Canageek
    • DialMforMara
    • varx
    • Harp the Wigglytuff

    @wigglytuffitout @DialMforMara @varx The paper is at https://doi.org/10.1126/science.3018924 but even my university doesn't have access to it without an inter-library loan. However, it is mentioned within this 1992 PNAS paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC50308/

    In conversation Saturday, 20-Jul-2019 23:28:55 EDT from cybre.space permalink

    Attachments

    1. File without filename could not get a thumbnail source.
      The site of attachment in human rhinovirus 14 for antiviral agents that inhibit uncoating
      from Science
      WIN 51711 and WIN 52084 are structurally related, antiviral compounds that inhibit the replication of rhino (common cold) viruses and related picornaviruses. They prevent the pH-mediated uncoating of the viral RNA. The compounds consist of a 3-methylisoxazole group that inserts itself into the hydrophobic interior of the VP1 beta-barrel, a connecting seven-membered aliphatic chain, and a 4-oxazolinylphenoxy group (OP) that covers the entrance to an ion channel in the floor of the "canyon." Viral disassembly may be inhibited by preventing the collapse of the VP1 hydrophobic pocket or by blocking the flow of ions into the virus interior.
    2. Acid-induced structural changes in human rhinovirus 14: possible role in uncoating.
      from PubMed Central (PMC)
      X-ray diffraction data were collected from human rhinovirus 14 crystals a few minutes after exposure to acid vapor and prior to excessive crystalline disorder. Conformational changes occurred (i) in the GH loop of viral protein (VP) 1, (ii) at the ion ...
  19. Canageek (canageek@cybre.space)'s status on Saturday, 20-Jul-2019 23:23:03 EDT Canageek Canageek
    • DialMforMara
    • varx
    • Harp the Wigglytuff

    @wigglytuffitout @DialMforMara @varx It was a memorial crystallography talk for Michael G. Rossmann, I think the section by Rui Zhao. The binding site for the cold is buried in a deep chasm, first seen by Rossmann's group, and he theorized the binding site was buried deep in that chasm, which is why it could mutate its surface into so many forms while doing basically the same thing. This was later proved correct, and they made a drug that targeted that binding site in 1986.

    In conversation Saturday, 20-Jul-2019 23:23:03 EDT from cybre.space permalink
  20. DialMforMara (dialmformara@wandering.shop)'s status on Saturday, 20-Jul-2019 19:29:56 EDT DialMforMara DialMforMara
    • Canageek

    Apparently a cure for the common cold was discovered in the mid-80s, but nobody uses it because it interacts badly with hormonal birth control.

    This fun fact brought to you by the science conference @Canageek is at, which is holding a memorial session for the crystallographer who discovered it.

    I wonder if, now that more people in North America are using non-hormonal birth control, they'll start working on it again

    In conversation Saturday, 20-Jul-2019 19:29:56 EDT from wandering.shop permalink Repeated by canageek
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